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In terms of the immune response, our secretome analysis revealed enrichment of immune-related pathways under oxidative stress, with qPCR confirming increased expression of inflammatory mediators IL-6, IL-11, and IL-18 shortly after H 2 O 2 treatment

Peer-reviewed data 2 on peptide therapy show that it may affect the entire nitric oxide (NO) system

no regulatory approval for clinical therapy

This in turn upregulates VEGFC proteolysis and induces lymphangiogenesis in a CRC cell-derived xenograft model in vivo

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